Fig. 2　Changes in chest computed tomography (CT) images of Patient 1. (a) Nodular shadows are scattered immediately beneath the pleura of both lungs at the time of the diagnosis of lymphoproliferative disorder (LPD). (b) The nodular shadows in lungs were reduced markedly 4 months after discontinuation of MTX. (c) The nodular shadows had almost disappeared 17 months after discontinuation of MTX. (d) No recurrence of LPD 24 months later.