Fig. 2
Discrepancy of RFLP patterns of SmaI digested DNA between isolates from cerebrospinal fluid, blood, and nasopharynx of 4 patients. In all patients, a difference in the ~ 485kb fragment was observed in 1 of 3 strains(arrow).
Patient 1, the isolate from the blood showed a singleband shift of approximately +20kb;
patient 2, the strain from the cerebrospinal fluid showed a shift of approximately -20kb;
patients 10 and 22, strains from the nasopharynx showed a shift of approximately -20kb shift.
Lanes:
C, isolate from cerebrospinal fluid;
B, from blood;
N, from nasopharynx;
M, lambda ladder molecular size marker.